Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.

Defective insulin secretion in response to glucose is an important component of the beta cell dysfunction seen in type 2 diabetes. As mitochondrial oxidative phosphorylation plays a key role in glucose-stimulated insulin secretion (GSIS), oxygen-sensing pathways may modulate insulin release. The von...

Full description

Bibliographic Details
Main Authors:	Cantley, J, Selman, C, Shukla, D, Abramov, A, Forstreuter, F, Esteban, M, Claret, M, Lingard, S, Clements, M, Harten, S, Asare-Anane, H, Batterham, R, Herrera, P, Persaud, S, Duchen, MR, Maxwell, P, Withers, D
Format:	Journal article
Language:	English
Published:	2009

Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.

Similar Items