Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS study.

SLCO1B1 gene variants are associated with severe statin-induced myopathy. We examined whether these variants are also associated with general statin intolerance in a large population of patients with type 2 diabetes receiving statins as part of routine clinical care. A total of 4,196 individuals wer...

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Váldodahkkit: Donnelly, L, Doney, A, Tavendale, R, Lang, C, Pearson, E, Colhoun, H, McCarthy, M, Hattersley, A, Morris, A, Palmer, C
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2011