T cell activation by anti-T3 antibodies: comparison of IgG1 and IgG2b switch variants and direct evidence for accessory function of macrophage Fc receptors.

The human T3 antigen is closely associated with the T cell receptor. Some anti-T3 antibodies cause T cell proliferation in the presence of monocytes which have Fc receptors (FcR) that bind particular antibody subclasses. Such an interaction is thought to determine whether or not an anti-T3 antibody...

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Bibliographic Details
Main Authors: Smith, K, Austyn, J, Hariri, G, Beverley, P, Morris, P
Format: Journal article
Language:English
Published: 1986