Genotype-phenotype association and biochemical analyses of glucose-6-phosphate dehydrogenase variants: Implications for the hemolytic risk of using 8-aminoquinolines for radical cure

<p><strong>Background:</strong> <em>Plasmodium vivax</em> remains the malaria species posing a major threat to human health worldwide owing to its relapse mechanism. Currently, the only drugs of choice for radical cure are the 8-aminoquinolines (primaquine and tafenoqui...

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Detalhes bibliográficos
Principais autores: Sudsumrit, S, Chamchoy, K, Songdej, D, Adisakwattana, P, Krudsood, S, Adams, ER, Imwong, M, Leartsakulpanich, U, Boonyuen, U
Formato: Journal article
Idioma:English
Publicado em: Frontiers Media 2022