Conjugate addition of lithium N-phenyl-N-(α-methylbenzyl)amide: application to the asymmetric synthesis of (R)-(-)-angustureine.

The conjugate addition of lithium (R)-N-phenyl-N-(α-methylbenzyl)amide to a range of α,β-unsaturated 4-methoxyphenyl esters proceeds with excellent levels of diastereoselectivity to give the corresponding β-amino esters in good yield and as single diastereoisomers (>99:1 dr). The synthetic ut...

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Những tác giả chính: Bentley, SA, Davies, S, Lee, J, Roberts, P, Thomson, J
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2011