Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts

Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts

<p>Myelodysplastic syndromes with ring sideroblasts (MDS-RS) commonly develop from hematopoietic stem cells (HSC) bearing mutations in the splicing factor <i>SF3B1</i> (<i>SF3B1</i><sup>mt</sup>). Direct studies into MDS-RS pathobiology have been limited by...

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Bibliographic Details
Main Authors: Moura, PL, Mortera Blanco, T, Hofman, IJ, Todisco, G, Kretzschmar, WW, Björklund, A-C, Creignou, M, Hagemann-Jensen, M, Ziegenhain, C, Cabrerizo Granados, D, Barbosa, I, Walldin, G, Jansson, M, Ashley, N, Mead, AJ, Lundin, V, Dimitriou, M, Yoshizato, T, Woll, PS, Ogawa, S, Sandberg, R, Jacobsen, S-EW, Hellström-Lindberg, E
Format: Journal article
Language:English
Published: American Association for Cancer Research 2023

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