Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys

Strategies to treat Zika virus (ZIKV) infection in dengue virus (DENV)-endemic areas are urgently needed. Here we show that a DENV-specific antibody against the E-dimer epitope (EDE) potently cross-neutralizes ZIKV and provides robust therapeutic efficacy as well as prophylactic efficacy against ZI...

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Bibliographic Details
Main Authors: Abbink, P, Larocca, R, Dejnirattisai, W, Screaton, G
Format: Journal article
Published: Springer Nature 2018