Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor.

The haptoglobin-haemoglobin receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in the bloodstream of the mammalian host, allowing it to acquire haem through the uptake of haptoglobin-haemoglobin complexes. Here we show that in Trypanosoma congolense th...

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Bibliographic Details
Main Authors: Lane-Serff, H, MacGregor, P, Peacock, L, Macleod, O, Kay, C, Gibson, W, Higgins, M, Carrington, M
Format: Journal article
Language:English
Published: eLife Sciences Publications 2016