Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor.

Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor.

The haptoglobin-haemoglobin receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in the bloodstream of the mammalian host, allowing it to acquire haem through the uptake of haptoglobin-haemoglobin complexes. Here we show that in Trypanosoma congolense th...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Lane-Serff, H, MacGregor, P, Peacock, L, Macleod, O, Kay, C, Gibson, W, Higgins, M, Carrington, M
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	eLife Sciences Publications 2016

Παρόμοια τεκμήρια

A receptor's tale: An eon in the life of a trypanosome receptor
ανά: Higgins, M, κ.ά.
Έκδοση: (2017)

Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity.
ανά: Higgins, M, κ.ά.
Έκδοση: (2013)

Structural basis of haptoglobin-haemoglobin scavenging by CD163
ανά: Zhou, X
Έκδοση: (2024)

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies
ανά: Macleod, OJS, κ.ά.
Έκδοση: (2020)

Distribution and diversity of the haemoglobin-haptoglobin iron-acquisition systems in pathogenic and non-pathogenic Neisseria.
ανά: Harrison, O, κ.ά.
Έκδοση: (2013)

Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana District of Ghana.
ανά: Ghansah, A, κ.ά.
Έκδοση: (2012)

Sickle haemoglobin, haemoglobin C and malaria mortality feedbacks
ανά: Goncalves, B, κ.ά.
Έκδοση: (2016)

Variation and molecular evolution of HmbR, the Neisseria meningitidis haemoglobin receptor
ανά: Evans, N, κ.ά.
Έκδοση: (2010)

Fetal haemoglobin and malaria
ανά: Pasvol, G, κ.ά.
Έκδοση: (1978)

The synthesis of haemoglobin E
ανά: Synodinos, J, κ.ά.
Έκδοση: (1981)

Structural insights into innate immunity against African trypanosomes
ανά: Lane-Serff, H
Έκδοση: (2017)

Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion
ανά: Trevor, C, κ.ά.
Έκδοση: (2019)

Haemoglobin and flow-mediated vasodilation.
ανά: Madsen, P, κ.ά.
Έκδοση: (2006)

Origin of complexity in haemoglobin evolution
ανά: Pillai, AS, κ.ά.
Έκδοση: (2020)

Haemoglobin S and haemoglobin C: 'quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria.
ανά: Modiano, D, κ.ά.
Έκδοση: (2008)

Novel alpha haemoglobin haplotypes in horses.
ανά: Bowling, A, κ.ά.
Έκδοση: (1988)

Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence.
ανά: Tauseef, I, κ.ά.
Έκδοση: (2011)

Molecular Characterisation of Haemoglobin constant spring and Haemoglobin Quong Sze with a combine-amplification refractory mutation system
ανά: Wee, Y.C., κ.ά.
Έκδοση: (2009)

Molecular characterisation of Haemoglobin Constant Spring and Haemoglobin Quong Sze with a combine-amplification refractory mutation system
ανά: Wee, Yong Chui, κ.ά.
Έκδοση: (2009)

Molecular epidemiology of the thalassaemias (including haemoglobin E).
ανά: Hill, A
Έκδοση: (1992)

Haemoglobin E beta thalassaemia in Sri Lanka.
ανά: Premawardhena, A, κ.ά.
Έκδοση: (2005)

Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia
ανά: Cronqvist, T, κ.ά.
Έκδοση: (2014)

The ancestral flower of angiosperms and its early diversification.
ανά: Sauquet, H, κ.ά.
Έκδοση: (2017)

The evolutionary and clinical implications of the uneven distribution of the frequency of the inherited haemoglobin variants over short geographical distances.
ανά: Premawardhena, A, κ.ά.
Έκδοση: (2016)

Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites.
ανά: Ponsuwanna, P, κ.ά.
Έκδοση: (2016)

Haemoglobin Adana in alpha thalassaemia intermedia in the Malaysian population
ανά: Lee, Tze Yan
Έκδοση: (2017)

Rare cases of haemoglobin variant presented with isolated erythrocytosis
ανά: Nahanthiran, Subithira, κ.ά.
Έκδοση: (2020)

Polymorphism of Haemoglobin-e in Selected Malaysian and the Maldives Populations
ανά: Saleem, Mohamed
Έκδοση: (2011)

Comparison of lead and cadmium chloride poisoning on bovine haemoglobin
ανά: Noor Azlan, Najihah, κ.ά.
Έκδοση: (2020)

International values for haemoglobin distributions in healthy pregnant women
ανά: Ohuma, EO, κ.ά.
Έκδοση: (2020)

The distribution of haemoglobin C and its prevalence in newborns in Africa
ανά: Piel, F, κ.ά.
Έκδοση: (2013)

Haemoglobin S and haemoglobin C: 'quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria (vol 17, pg 789, 2008)
ανά: Modiano, D, κ.ά.
Έκδοση: (2008)

Monitoring haemoglobin status in dengue patients using ARMAX model
ανά: Abdul Rahim, H., κ.ά.
Έκδοση: (2008)

Haemoglobin Lepore in a Malay Family: A Case Report
ανά: Pasangna, J., κ.ά.
Έκδοση: (2005)

The significance of borderline haemoglobin A₂ level among Kelantan population
ανά: Sehat, Nani Shahida
Έκδοση: (2016)

The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria.
ανά: Lee, S, κ.ά.
Έκδοση: (2008)

Non-deletion haemoglobin H disease in Papua New Guinea.
ανά: Hill, A, κ.ά.
Έκδοση: (1987)

Direct In Vivo Electrochemical Detection of Haemoglobin in Red Blood Cells
ανά: Toh, Rou Jun, κ.ά.
Έκδοση: (2014)

Genetic determinants of jaundice and gallstones in haemoglobin E beta thalassaemia.
ανά: Premawardhena, A, κ.ά.
Έκδοση: (2001)

Genetic Disorders of Human Haemoglobin as Models for Analysing Gene Regulation
ανά: Weatherall, D, κ.ά.
Έκδοση: (1984)