Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy.
In female mammals, one of the two X chromosomes is transcriptionally silenced to equalize X-linked gene dosage relative to XY males, a process termed X chromosome inactivation. Mechanistically, this is thought to occur via directed recruitment of chromatin modifying factors by the master regulator,...
| Autors principals: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
2014
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