Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy.

In female mammals, one of the two X chromosomes is transcriptionally silenced to equalize X-linked gene dosage relative to XY males, a process termed X chromosome inactivation. Mechanistically, this is thought to occur via directed recruitment of chromatin modifying factors by the master regulator,...

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Bibliographic Details
Main Authors: Cerase, A, Smeets, D, Tang, Y, Gdula, M, Kraus, F, Spivakov, M, Moindrot, B, Leleu, M, Tattermusch, A, Demmerle, J, Nesterova, T, Green, C, Otte, A, Schermelleh, L, Brockdorff, N
Format: Journal article
Language:English
Published: 2014

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