Disrupting protein-protein interactions with non-peptidic, small molecule alpha-helix mimetics.
Many biological processes are regulated by protein-protein interactions (PPIs) and as such their misregulation can cause a multitude of diseases. Often the interactions between large proteins are mediated by small protein secondary structural domains, which project a minimum number of specifically a...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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