Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and mice

Peripheral sensitization during inflammatory pain is mediated by a variety of endogenous proalgesic mediators including a number of oxidized lipids, some of which serve endogenous modulators of sensory TRP-channels. These lipids are eicosanoids of the arachidonic acid and linoleic acid pathway, as w...

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Main Authors: Sisignano, M, Angioni, C, Ferreiros, N, Schuh, C, Suo, J, Schreiber, Y, Dawes, J, Antunes-Martins, A, Bennett, D, McMahon, S, Geisslinger, G, Scholich, K
Format: Journal article
Language:English
Published: Public Library of Science 2013