The observed T cell receptor space database enables paired-chain repertoire mining, coherence analysis and language modelling

T cell activation is governed through T cell receptors (TCRs), heterodimers of two sequence-variable chains (often an α and β chain) that synergistically recognize antigen fragments presented on cell surfaces. Despite this, there only exist repositories dedicated to collecting single-chain, not pair...

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Bibliographic Details
Main Authors: Raybould, MIJ, Greenshields-Watson, A, Agarwal, P, Aguilar-Sanjuan, B, Olsen, TH, Turnbull, OM, Quast, NP, Deane, CM
Format: Journal article
Language:English
Published: Cell Press 2024