The observed T cell receptor space database enables paired-chain repertoire mining, coherence analysis and language modelling
T cell activation is governed through T cell receptors (TCRs), heterodimers of two sequence-variable chains (often an α and β chain) that synergistically recognize antigen fragments presented on cell surfaces. Despite this, there only exist repositories dedicated to collecting single-chain, not pair...
Auteurs principaux: | Raybould, MIJ, Greenshields-Watson, A, Agarwal, P, Aguilar-Sanjuan, B, Olsen, TH, Turnbull, OM, Quast, NP, Deane, CM |
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Format: | Journal article |
Langue: | English |
Publié: |
Cell Press
2024
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