Molecular mechanisms of hedgehog signal transduction by the G-protein coupled receptor smoothened

<p>The Hedgehog signalling pathway is an essential developmental pathway present in all bilaterians that is involved in embryogenesis, body patterning and stem cell homeostasis. Dysregulation of the Hh pathway leads to various kinds of cancer, such as basal cell carcinoma and medulloblastoma....

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Bibliographic Details
Main Author: Byrne, E
Other Authors: Siebold, C
Format: Thesis
Language:English
Published: 2017
Subjects: