Rad25p, a DNA helicase subunit of yeast transcription factor TFIIH, is required for promoter escape in vivo.
The general transcription factor TFIIH is required for initial DNA unwinding and promoter escape by RNA polymerase II in vitro. We examined whether Rad25p, a DNA helicase subunit of TFIIH, mediates promoter opening and promoter escape in the yeast Saccharomyces cerevisiae. DNA unwinding was probed w...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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