iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe.

PURPOSE: iASPP is a specific regulator of p53-mediated apoptosis. Herein, we provided the first report on the expression profile of iASPP in ovarian epithelial tumor and its effect on paclitaxel chemosensitivity. EXPERIMENTAL DESIGN: Expression and amplification status of iASPP was examined in 203...

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Bibliographic Details
Main Authors: Jiang, L, Siu, M, Wong, O, Tam, K, Lu, X, Lam, E, Ngan, H, Le, X, Wong, E, Monteiro, L, Chan, H, Cheung, A
Format: Journal article
Language:English
Published: 2011