The spectrum of neutralizing and non-neutralizing anti-FVIII antibodies in a nationwide cohort of 788 persons with hemophilia A

Objectives: Anti-factor VIII (FVIII) antibodies have been reported to exhibit both neutralizing and non-neutralizing characteristics. This is the first study investigating the full spectrum of FVIII-specific antibodies, including non-neutralizing antibodies, very-low titer inhibitors, and inhibitors...

Full description

Bibliographic Details
Main Authors: Oomen, I, Verhagen, M, Miranda, M, Allacher, P, Beckers, EAM, Blijlevens, NMA, Bom, JGVD, Coppens, M, Driessens, M, Eikenboom, JCJ, Fijnvandraat, K, Hassan, S, van Heerde, WL, Hooimeijer, HL, Jansen, JH, Kaijen, P, Leebeek, FWG, Meijer, D, Paul, H, Rijpma, SR, Rosendaal, FR, Smit, C, van Vulpen, LFD, Voorberg, J
Format: Journal article
Language:English
Published: Frontiers Media 2024