Use of trifluoroacetaldehyde N-tfsylhydrazone as a trifluorodiazoethane surrogate and its synthetic applications

Trifluorodiazoethane (CF3CHN2), a highly reactive fluoroalkylating reagent, offers a useful means to introduce trifluoromethyl groups into organic molecules. At present, CF3CHN2 can only be generated by oxidation of trifluoroethylamine hydrochloride under acidic conditions; due to its toxic and expl...

Full description

Bibliographic Details
Main Authors: Zhang, X, Liu, Z, Yang, X, Dong, Y, Virelli, M, Zanoni, G, Anderson, E, Bi, X
Format: Journal article
Language:English
Published: Springer Nature 2019