Role of cell-penetrating peptides in intracellular delivery of peptide nucleic acids targeting hepadnaviral replication

Peptide nucleic acids (PNAs) are potentially attractive antisense agents against hepatitis B virus (HBV), although poor cellular uptake limits their therapeutic application. In the duck HBV (DHBV) model, we evaluated different cell-penetrating peptides (CPPs) for delivery to hepatocytes of a PNA-tar...

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Bibliographic Details
Main Authors: Ndeboko, B, Ramamurthy, N, Lemamy, G, Jamard, C, Nielsen, P, Cova, L
Format: Journal article
Language:English
Published: Elsevier 2017