Role of cell-penetrating peptides in intracellular delivery of peptide nucleic acids targeting hepadnaviral replication
Peptide nucleic acids (PNAs) are potentially attractive antisense agents against hepatitis B virus (HBV), although poor cellular uptake limits their therapeutic application. In the duck HBV (DHBV) model, we evaluated different cell-penetrating peptides (CPPs) for delivery to hepatocytes of a PNA-tar...
Main Authors: | Ndeboko, B, Ramamurthy, N, Lemamy, G, Jamard, C, Nielsen, P, Cova, L |
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格式: | Journal article |
语言: | English |
出版: |
Elsevier
2017
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