Metabolic perturbations in the pathogenesis of hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) has been informative as a genetic model of cardiac hypertrophy. Unexpectedly, analysis of the diverse sarcomeric mutations that typically cause HCM has implicated energetic compromise in pathogenesis. Mutations in a regulatory subunit of AMP-activated protein kinase...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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