DNA-recognition process described by MD simulations of the lactose repressor protein on a specific and a non-specific DNA sequence.

The lactose repressor protein may bind DNA in two possible configurations: a specific one, if the DNA sequence corresponds to a binding site, and a non-specific one otherwise. To find its target sequences, the lactose repressor first binds non-specifically to DNA, and subsequently, it rapidly search...

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Bibliographic Details
Main Authors: Furini, S, Barbini, P, Domene, M
Format: Journal article
Language:English
Published: 2013