DNA-recognition process described by MD simulations of the lactose repressor protein on a specific and a non-specific DNA sequence.
The lactose repressor protein may bind DNA in two possible configurations: a specific one, if the DNA sequence corresponds to a binding site, and a non-specific one otherwise. To find its target sequences, the lactose repressor first binds non-specifically to DNA, and subsequently, it rapidly search...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2013
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