XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.

XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.

X-ray repair cross-complementing protein-1 (XRCC1)-deficient cells are sensitive to DNA damaging agents and have delayed processing of DNA base lesions. In support of its role in base excision repair, it was found that XRCC1 forms a tight complex with DNA ligase IIIalpha and also interacts with DNA...

Bibliografski detalji
Glavni autori:	Dianova, I, Sleeth, K, Allinson, S, Parsons, J, Breslin, C, Caldecott, K, Dianov, G
Format:	Journal article
Jezik:	English
Izdano:	2004

Slični predmeti

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
od: Parsons, J, i dr.
Izdano: (2005)

Repair of abasic sites in DNA.
od: Dianov, G, i dr.
Izdano: (2003)

XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.
od: Parsons, J, i dr.
Izdano: (2010)

Orchestration of base excision repair by controlling the rates of enzymatic activities.
od: Allinson, S, i dr.
Izdano: (2004)

Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts.
od: Parsons, J, i dr.
Izdano: (2005)

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
od: Parsons, J, i dr.
Izdano: (2008)

Exchangeability of mammalian DNA ligases between base excision repair pathways.
od: Sleeth, K, i dr.
Izdano: (2004)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
od: Parsons, J, i dr.
Izdano: (2011)

Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.
od: Chan, K, i dr.
Izdano: (2007)

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
od: Yang, J, i dr.
Izdano: (2010)

Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks.
od: Woodhouse, B, i dr.
Izdano: (2008)

Role of a BRCT domain in the interaction of DNA ligase III-alpha with the DNA repair protein XRCC1.
od: Taylor, R, i dr.
Izdano: (1998)

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
od: Ström, C, i dr.
Izdano: (2011)

A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair.
od: Taylor, R, i dr.
Izdano: (2000)

Monitoring base excision repair proteins on damaged DNA using human cell extracts.
od: Parsons, J, i dr.
Izdano: (2004)

USP7/HAUSP stimulates repair of oxidative DNA lesions.
od: Khoronenkova, S, i dr.
Izdano: (2011)

XRCC1 and base excision repair balance in response to nitric oxide
od: Svilar, David, i dr.
Izdano: (2017)

APE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanine.
od: Parsons, J, i dr.
Izdano: (2005)

Co-ordination of base excision repair and genome stability.
od: Parsons, J, i dr.
Izdano: (2013)

Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
od: Chen, X, i dr.
Izdano: (2018)

DNA repair fidelity of base excision repair pathways in human cell extracts.
od: Zhang, Q, i dr.
Izdano: (2005)

In vitro base excision repair using mammalian cell extracts.
od: Parsons, J, i dr.
Izdano: (2012)

DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts
od: Braithwaite, Elena K., i dr.
Izdano: (2011)

DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts.
od: Elena K Braithwaite, i dr.
Izdano: (2010-08-01)

Polymorphisms of the DNA repair genes XRCC1 and XRCC3 in a Brazilian population
od: Márcia Cristina Duarte, i dr.
Izdano: (2005-09-01)

DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions.
od: Parsons, J, i dr.
Izdano: (2007)

Genetic polymorphisms in DNA base excision repair gene <it>XRCC1 </it>and the risk of squamous cell carcinoma of the head and neck
od: Pietruszewska Wioletta, i dr.
Izdano: (2009-03-01)

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
od: Parsons, J, i dr.
Izdano: (2009)

Polymorphisms in DNA repair genes XRCC2 and XRCC3 risk of gastric cancer in Turkey
od: İlhami Gok, i dr.
Izdano: (2014-09-01)

DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment?
od: Poletto, M, i dr.
Izdano: (2017)

Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer
od: S. S. Rakitin, i dr.
Izdano: (2011-12-01)

Polymorphie DNA repair genes XRCC1 and XRCC3 and the risk for cervical cancer in Brazilian patients
od: Fabricio Colacino-Silva, i dr.
Izdano: (2017-01-01)

Monitoring base excision repair by in vitro assays.
od: Dianov, G
Izdano: (2003)

Base excision repair targets for cancer therapy.
od: Dianov, G
Izdano: (2011)

Isolation of a small molecule inhibitor of DNA base excision repair.
od: Madhusudan, S, i dr.
Izdano: (2005)

The importance of XRCC2 in RAD51-related DNA damage repair.
od: Tambini, C, i dr.
Izdano: (2010)

DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta.
od: Sarkar, S, i dr.
Izdano: (2006)

Base excision repair fidelity in normal and cancer cells.
od: Chan, K, i dr.
Izdano: (2006)

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.
od: Markkanen, E, i dr.
Izdano: (2012)

Mammalian base excision repair: the forgotten archangel.
od: Dianov, G, i dr.
Izdano: (2013)