Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice.

We recently demonstrated that reducing IGF-1 receptor (IGF-1R) numbers in the endothelium enhances nitric oxide (NO) bioavailability and endothelial cell insulin sensitivity. In the present report, we aimed to examine the effect of increasing IGF-1R on endothelial cell function and repair. To examin...

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Bibliographic Details
Main Authors:	Imrie, H, Viswambharan, H, Sukumar, P, Abbas, A, Cubbon, R, Yuldasheva, N, Gage, M, Smith, J, Galloway, S, Skromna, A, Rashid, S, Futers, T, Xuan, S, Gatenby, V, Grant, P, Channon, K, Beech, D, Wheatcroft, S, Kearney, M
Format:	Journal article
Language:	English
Published:	American Diabetes Association 2012

Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice.

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