A biased agonist at immunometabolic receptor GPR84 causes distinct functional effects in macrophages
GPR84 is an orphan G protein-coupled receptor which is expressed on immune cells and implicated in several inflammatory diseases. The validation of GPR84 as a therapeutic target is hindered by the narrow range of available chemical tools and consequent poor understanding of GPR84 pathophysiology. He...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
American Chemical Society
2019
|