Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease.

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease.

The presentation pathways by which allogeneic peptides induce graft-versus-host disease (GVHD) are unclear. We developed a bone marrow transplant (BMT) system in mice whereby presentation of a processed recipient peptide within major histocompatibility complex (MHC) class II molecules could be spati...

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Bibliographic Details
Main Authors: Koyama, M, Kuns, R, Olver, S, Raffelt, N, Wilson, Y, Don, A, Lineburg, K, Cheong, M, Robb, R, Markey, K, Varelias, A, Malissen, B, Hämmerling, G, Clouston, A, Engwerda, C, Bhat, P, MacDonald, K, Hill, G
Format: Journal article
Language:English
Published: 2012

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