Does levodopa accelerate the pathologic process in Parkinson disease brain?
<p>Background: Several in vitro studies have suggested levodopa (L-dopa) to be toxic to dopaminergic neurons and that it can modulate the aggregation process of α-synuclein. We investigated the relationship between cumulative lifetime dose of L-dopa and nigral neuronal count and Lewy body (LB)...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Academy of Neurology
2011
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