The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection
<p>Despite the introduction of antiretroviral therapy, the HIV/HIV epidemic remains an unsolved global health problem. Amongst all the host defence mechanisms, HLA class I molecules have shown the strongest genetic association with delayed disease progression, in particular HLA-B alleles. N...
Main Author: | |
---|---|
Other Authors: | |
Format: | Thesis |
Published: |
2017
|
Subjects: |