The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

<p>Despite the introduction of antiretroviral therapy, the HIV/HIV epidemic remains an unsolved global health problem. Amongst all the host defence mechanisms, HLA class I molecules have shown the strongest genetic association with delayed disease progression, in particular HLA-B alleles. N...

Ausführliche Beschreibung

Bibliographische Detailangaben
1. Verfasser: Tsai, M
Weitere Verfasser: Goulder, P
Format: Abschlussarbeit
Veröffentlicht: 2017
Schlagworte: