The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

<p>Despite the introduction of antiretroviral therapy, the HIV/HIV epidemic remains an unsolved global health problem. Amongst all the host defence mechanisms, HLA class I molecules have shown the strongest genetic association with delayed disease progression, in particular HLA-B alleles. N...

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Dettagli Bibliografici
Autore principale:	Tsai, M
Altri autori:	Goulder, P
Natura:	Tesi
Pubblicazione:	2017
Soggetti:	HIV infections > Immunological aspects

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