The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

<p>Despite the introduction of antiretroviral therapy, the HIV/HIV epidemic remains an unsolved global health problem. Amongst all the host defence mechanisms, HLA class I molecules have shown the strongest genetic association with delayed disease progression, in particular HLA-B alleles. N...

Descripció completa

Dades bibliogràfiques
Autor principal:	Tsai, M
Altres autors:	Goulder, P
Format:	Thesis
Publicat:	2017
Matèries:	HIV infections > Immunological aspects

Ítems similars

HLA-B51 associated HIV-1 viral control
per: Peng, Y
Publicat: (2013)

Exploiting the use of induced pluripotent stem cell derived immune cells for immunotherapy
per: Sachamitr, S
Publicat: (2015)

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection
per: Daniel M. Muema, et al.
Publicat: (2020-03-01)

Platelets in Immune Response to Virus and Immunopathology of Viral Infections
per: Eugenio D. Hottz, et al.
Publicat: (2018-04-01)

Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HBV Replication through Production of IFN-γ and TNF-⍺
per: Mohammad Haque, et al.
Publicat: (2020-07-01)

Evolution of HLA-B*5703 HIV-1 escape mutations and their impact on HIV-1 replicative capacity
per: Crawford, H, et al.
Publicat: (2009)

Population-specific HLA impact in immune control of HIV in Mexico and non-Mexican HIV infected cohorts
per: Juarez Molina, CI
Publicat: (2014)

A functional and structural study of HLA-B*2705 restricted CTL responses associated with delayed HIV-1 disease progression
per: Pymm, PG
Publicat: (2012)

Corrigendum: Functional Mechanisms of Treg in the Context of HIV Infection and the Janus Face of Immune Suppression
per: Jacobo López-Abente, et al.
Publicat: (2018-04-01)

A study of the phenotype and function of HLA-C restricted CD8 T cells in HIV-1 infection
per: Corrah, TW
Publicat: (2011)

TCF-1 regulates HIV-specific CD8+ T cell expansion capacity
per: Rachel L. Rutishauser, et al.
Publicat: (2021-02-01)

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells
per: Wouter A. van der Heijden, et al.
Publicat: (2021-04-01)

Gastrointestinal immune responses in HIV infected subjects
per: LRR Castello-Branco, et al.
Publicat: (1996-06-01)

Possibilities of speciﬁc immunological tests in patients with TB/HIV coinfection
per: L. N. Motanova, et al.
Publicat: (2021-11-01)

Pediatric HIV Infection Findings At The Time Of Diagnosis In A Tertiary Care Center In Turkey
per: Neslihan Mete Atasever, et al.
Publicat: (2024-12-01)

P09-17. Evolution of HLA-B*5703 HIV-1 escape mutations and their impact on HIV-1 replicative capacity
per: Crawford, H, et al.
Publicat: (2009)

Molecular mechanisms underlying the pathogenesis of dengue fever: dengue virus co-opts innate type 2 pathways to escape early control of viral replication
per: Fonseka, CL
Publicat: (2022)

Impact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacity.
per: Wright, J, et al.
Publicat: (2012)

Immunosenescence in HIV infection
per: Glenn, W
Publicat: (2016)

Impact of etiotropic therapy on the immune status of patients with HIV infection and tuberculosis
per: V N Zimina, et al.
Publicat: (2015-11-01)

Supplementary figures for "Inhibiting HLA-B27 homdimer-driven immune cell inflammation in Spondyloarthritis"
per: Bowness, P
Publicat: (2012)

Characterisation of the HIV-1 reservoir and the potential for viral eradication
per: Williams, J, et al.
Publicat: (2014)

Epidemiological and viral characteristics of undiagnosed HIV infections in Botswana
per: Lynnette Bhebhe, et al.
Publicat: (2022-08-01)

Virus-induced lncRNA-BTX allows viral replication by regulating intracellular translocation of DHX9 and ILF3 to induce innate escape
per: Yang Cao, et al.
Publicat: (2023-10-01)

SARS-CoV-2 infection does not induce HIV viral escape in the central nervous system: A case series
per: C. Pinnetti, et al.
Publicat: (2020-12-01)

Public T cell clonotypes are selected in HLA-B∗57:01+/HIV+ patients independently of the viral load
per: Demetra S.M. Chatzileontiadou, et al.
Publicat: (2024-08-01)

Early infant diagnosis of HIV infection at the John F. Kennedy Medical Center, Monrovia, Liberia
per: Umar I. U, et al.
Publicat: (2022-12-01)

HIV-1 induction of macrophage immune mediators
per: Dacon, C
Publicat: (2019)

Development and the HIV epidemic : a forward-looking evaluation of the approach of the UNDP HIV and Development Programme /
per: Parnell, Bruce
Publicat: (1996)

THE INFLUENCE OF HIV INFECTION DURATION BEFORE ANTIRETROVIRAL THERAPY ON IMMUNOLOGICAL TREATMENT FAILURE
per: A. F. Oleynik, et al.
Publicat: (2017-06-01)

Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region
per: Samara Tatielle Monteiro Gomes, et al.
Publicat: (2020-07-01)

Anti-HIV antibody development up to 1 year after antiretroviral therapy initiation in acute HIV infection
per: Julie L. Mitchell, et al.
Publicat: (2022-01-01)

Immunological interaction during helminth and HIV co-infection: Integrative research needs for sub-Saharan Africa
per: Miranda N. Mpaka-Mbatha, et al.
Publicat: (2023-01-01)

HLA DRB1 polymorphism and risk of HIV/tuberculosis co-infection.
per: L. R. Shostakovych-Koretskaya, et al.
Publicat: (2017-10-01)

Infection and Immunity /
per: 374694 Playfair, John, et al.
Publicat: (2008)

Infection and immunity /
per: 329569 Playfair, John H. L.
Publicat: (2004)

CTL escape and viral fitness in HIV/SIV infection
per: Sayuri eSeki, et al.
Publicat: (2012-01-01)

Peramalan jangkitan dan penyebaran virus HIV di Malaysia /
per: 181110 Siti Norbaya Shaharul Anwar, et al.
Publicat: (1996)

The impact of HIV/AIDS on children in Swaziland
per: Jones, L
Publicat: (2007)

Assessment of HIV-1 integration in tissues and subsets across infection stages
per: Vincent H. Wu, et al.
Publicat: (2020-12-01)