The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

<p>Despite the introduction of antiretroviral therapy, the HIV/HIV epidemic remains an unsolved global health problem. Amongst all the host defence mechanisms, HLA class I molecules have shown the strongest genetic association with delayed disease progression, in particular HLA-B alleles. N...

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Bibliografiske detaljer
Hovedforfatter:	Tsai, M
Andre forfattere:	Goulder, P
Format:	Thesis
Udgivet:	2017
Fag:	HIV infections > Immunological aspects

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af: Williams, J, et al.
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