The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection

<p>Despite the introduction of antiretroviral therapy, the HIV/HIV epidemic remains an unsolved global health problem. Amongst all the host defence mechanisms, HLA class I molecules have shown the strongest genetic association with delayed disease progression, in particular HLA-B alleles. N...

Cijeli opis

Bibliografski detalji
Glavni autor: Tsai, M
Daljnji autori: Goulder, P
Format: Disertacija
Izdano: 2017
Teme: