Thermal dissociation of multimeric protein complexes by using nanoelectrospray mass spectrometry.
The behavior of macromolecular systems at different temperatures is often crucial to their biological activity and function. While heat-induced changes of individual proteins are readily monitored by a number of spectroscopic methods, changes in noncovalent complexes of biomolecules are more challen...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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