Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice.
Insulin-like growth factor-II (IGF-II) is an embryonic growth promoter and cell survival factor. IGF-II supply is normally limited by gene expression because transcription occurs predominantly from the paternal allele in mouse and man (maternal imprinting). Excess IGF-II has detrimental systemic and...
| Main Authors: | , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2000
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