Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance

Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance

The increasing rate of antibiotic resistance and slowing discovery of novel antibiotic treatments presents a growing threat to public health. Here, we consider a simple model of evolution in asexually reproducing populations which considers adaptation as a biased random walk on a fitness landscape....

書誌詳細
主要な著者:	Nichol, D, Jeavons, P, Fletcher, A, Bonomo, R, Maini, P, Paul, J, Gatenby, R, Anderson, A, Scott, J
フォーマット:	Journal article
言語:	English
出版事項:	Public Library of Science 2015

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