Interaction of Avibactam with Class B Metallo-β-Lactamases.

β-Lactamases are the most important mechanisms of resistance to the β-lactam antibacterials. There are two mechanistic classes of β-lactamases: the serine β-lactamases (SBLs) and the zinc-dependent metallo-β-lactamases (MBLs). Avibactam, the first clinically useful non-β-lactam β-lactamase inhibitor...

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Detalhes bibliográficos
Principais autores: Abboud, M, Damblon, C, Brem, J, Smargiasso, N, Mercuri, P, Gilbert, B, Rydzik, A, Claridge, T, Schofield, C, Frère, J
Formato: Journal article
Idioma:English
Publicado em: American Society for Microbiology 2016