Cyclin A triggers mitosis either via the greatwall kinase pathway or cyclin B

Two mitotic cyclin types, cyclin A and B, exist in higher eukaryotes, but their specialised functions in mitosis are incompletely understood. Using degron tags for rapid inducible protein removal, we analyse how acute depletion of these proteins affects mitosis. Loss of cyclin A in G2‐phase prevents...

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Detaylı Bibliyografya
Asıl Yazarlar: Hégarat, N, Crncec, A, Suarez Peredo Rodriguez, MF, Echegaray Iturra, F, Gu, Y, Busby, O, Lang, PF, Barr, AR, Bakal, C, Kanemaki, MT, Lamond, AI, Novak, B, Ly, T, Hochegger, H
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: EMBO Press 2020
Konular: