Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility.

Several lines of evidence link glucose-6-phosphate dehydrogenase (G6PD) deficiency to protection from severe malaria. Early reports suggested most G6PD deficiency in sub-Saharan Africa was because of the 202A/376G G6PD A- allele, and recent association studies of G6PD deficiency have employed genoty...

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Hlavní autoři: Clark, T, Fry, A, Auburn, S, Campino, S, Diakite, M, Green, A, Richardson, A, Teo, Y, Small, K, Wilson, J, Jallow, M, Sisay-Joof, F, Pinder, M, Sabeti, P, Kwiatkowski, D, Rockett, K
Médium: Journal article
Jazyk:English
Vydáno: 2009