Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d molecules.

The glycolipid alpha-galactosylceramide (alpha-GalCer) is a potent activator of invariant natural killer T (iNKT) cells and has been shown to be an effective agent against cancer, infections and autoimmune diseases. The effectiveness of alpha-GalCer and its alkyl chain analogues depends on efficient...

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Bibliographic Details
Main Authors: Denkberg, G, Stronge, V, Zahavi, E, Pittoni, P, Oren, R, Shepherd, D, Salio, M, McCarthy, C, Illarionov, P, van der Merwe, A, Besra, G, Dellabona, P, Casorati, G, Cerundolo, V, Reiter, Y
Format: Journal article
Language:English
Published: 2008