Mechanisms of histone lysine-modifying enzymes: A computational perspective on the role of the protein environment

<p>Epigenetic pathways are involved in a wide range of diseases, including cancer and neurological disorders. Specifically, histone modifying and reading processes are the most broadly studied and are targeted by several licensed drugs. Although there have been significant advances in understa...

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Bibliographic Details
Main Authors: Cortopassi, WA, Kumar, K, Duarte, F, Pimentel, AS, Paton, R
Format: Journal article
Language:English
Published: Elsevier 2016