The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways.
We have assessed whether viscoelastic gels known to inhibit mucociliary clearance can increase lipid-mediated gene transfer. Methylcellulose or carboxymethylcellulose (0.25-1.5%) was mixed with complexes of the cationic lipid GL67A and plasmids encoding luciferase and perfused onto the nasal epithel...
Hlavní autoři: | , , , , , , , , , , , , , , , , , , , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2010
|