Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses.

Inflammatory lung disease is the major cause of morbidity and mortality in cystic fibrosis (CF); understanding what produces dysregulated innate immune responses in CF cells will be pivotal in guiding the development of novel anti-inflammatory therapies. To elucidate the molecular mechanisms that me...

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Bibliographic Details
Main Authors: Blohmke, C, Mayer, M, Tang, A, Hirschfeld, A, Fjell, C, Sze, M, Falsafi, R, Wang, S, Hsu, K, Chilvers, M, Hogg, J, Hancock, R, Turvey, SE
Format: Journal article
Language:English
Published: 2012