Interplay between oxygen sensing mechanisms and hepatitis B virus replication
<p>Hepatitis B virus (HBV) preferentially replicates in the liver, a naturally hypoxic organ with an oxygen gradient from 8-4% in the periportal and pericentral regions, respectively. The hypoxia inducible factor (HIF) pathway is the most well studied mammalian oxygen sensing mechanism and is...
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Format: | Thesis |
Language: | English |
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2021
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