Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

Bromodomains (BRDs) are evolutionarily conserved protein–protein interaction modules that are found in a wide range of proteins with diverse catalytic and scaffolding functions and are present in most tissues. BRDs selectively recognize and bind to acetylated Lys residues — particularly in histones...

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Bibliographic Details
Main Authors: Fujisawa, T, Filippakopoulos, P
Format: Journal article
Published: Nature Publishing Group 2017