Functions of bromodomain-containing proteins and their roles in homeostasis and cancer
Bromodomains (BRDs) are evolutionarily conserved protein–protein interaction modules that are found in a wide range of proteins with diverse catalytic and scaffolding functions and are present in most tissues. BRDs selectively recognize and bind to acetylated Lys residues — particularly in histones...
Main Authors: | Fujisawa, T, Filippakopoulos, P |
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Format: | Journal article |
Published: |
Nature Publishing Group
2017
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