Botulinum toxin-A treatment reduces human mechanical pain sensitivity and mechanotransduction.

The mechanisms underlying the analgesic effects of botulinum toxin serotype A (BoNT-A) are not well understood. We have tested the hypothesis that BoNT-A can block nociceptor transduction. Intradermal administration of BoNT-A to healthy volunteers produced a marked and specific decrease in noxious m...

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Bibliographic Details
Main Authors: Paterson, K, Lolignier, S, Wood, J, McMahon, S, Bennett, D
Format: Journal article
Language:English
Published: 2014