Intrapleural use of tissue plasminogen activator and DNase in pleural infection

BACKGROUND: More than 30% of patients with pleural infection either die or require surgery. Drainage of infected fluid is key to successful treatment, but intrapleural fibrinolytic therapy did not improve outcomes in an earlier, large, randomized trial. METHODS: We conducted a blinded, 2-by-2 factor...

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Bibliografiska uppgifter
Huvudupphovsmän: Rahman, N, Maskell, N, West, A, Teoh, R, Arnold, A, Mackinlay, C, Peckham, D, Davies, C, Ali, N, Kinnear, W, Bentley, A, Kahan, B, Wrightson, J, Davies, H, Hooper, C, Lee, Y, Hedley, E, Crosthwaite, N, Choo, L, Helm, E, Gleeson, F, Nunn, A, Davies, R
Materialtyp: Journal article
Språk:English
Publicerad: 2011